Heart analysis using pressure-controlled intermittent coronary s

Surgery – Truss – Pad

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61B 502

Patent

active

049694707

ABSTRACT:
The coronary sinus is intermittently occluded by use of means for occluding the sinus, a pressure transducer for sensing the fluid pressure within the sinus and providing corresponding fluid pressure signals, and a controller responsive to the transducer and arranged to provide trigger signals to the occluding means to trigger an occlusion and to interrupt the occlusion, the system being characterized in that the controller is arranged to estimate a plateau level of the fluid pressure during each occlusion and for providing a trigger signal to interrupt each occlusion on the basis of the estimate. The duration of the interruption before the next occlusion is controlled in response to the volume flow in the sinus during the interruption. Pharmacological agents are injected into the sinus during the occlusion, for retroperfusion to the heart tissue. An analysis of heart function is obtained by analyzing the local pressure maxima in successive heartbeats during occlusion. Initiation of the next occlusion is timed based on fluid pressure signals taken from the sinus during occlusion. The degree of tissue at risk of infarction (or the amount of infarcted tissue) is estimated based on the fluid pressure signals.

REFERENCES:
patent: 3064649 (1962-11-01), Fuson
patent: 3132643 (1964-05-01), Baum et al.
patent: 3425419 (1969-02-01), Dato
patent: 3468631 (1969-09-01), Kaible et al.
patent: 3498290 (1970-03-01), Shaw et al.
patent: 3610228 (1971-10-01), Temkin
patent: 3692018 (1972-09-01), Goetz et al.
patent: 3738372 (1973-06-01), Shioshvili
patent: 3847142 (1974-11-01), Williams, Jr. et al.
patent: 3893452 (1975-07-01), Birnbaum
patent: 3923060 (1975-12-01), Ellinwood, Jr.
patent: 3939820 (1976-02-01), Grayzel
patent: 3951140 (1976-04-01), Eggleton et al.
patent: 3985123 (1976-10-01), Herzlinger et al.
patent: 3995623 (1976-12-01), Blake et al.
patent: 4016871 (1977-04-01), Schiff
patent: 4069815 (1978-01-01), Lee
patent: 4080966 (1978-03-01), McNally et al.
patent: 4175264 (1979-11-01), Schiff
patent: 4245648 (1981-01-01), Trimmer et al.
patent: 4425920 (1984-01-01), Bourland et al.
patent: 4427009 (1984-01-01), Wells et al.
patent: 4456000 (1984-06-01), Schjeldahl et al.
patent: 4459977 (1984-07-01), Pizon et al.
patent: 4493697 (1985-01-01), Krause et al.
patent: 4689041 (1987-08-01), Corday et al.
Thornton et al., "Effect of Chronic Chardiac Venous Occlusion on Coronary Arterial and Cardiac Venous Hemodynamics", 9/30/89, Effects of Chronic Occlusion of Coronary Veins, pp. 181-184.
Beck, "Revascularization of the Heart", Surgery 26(1), 1949, pp. 82-88.
Hahn et al., "Revascularization of the Heart: Histologic Changes after Arterialization of the Coronary Sinus", Circulation, vol. V, Jun. 1952, pp. 810-815.
Eckstein et al., "Acute Effects of Elevation of Cornonary Sinus Pressure", Circulation, vol. VII, Mar. 1953, pp. 422-436.
Bakst et al., "Arterialization of the Coronary Sinus in Occlusive Coronary Artery Disease", J. Thoracie Surg., vol. 31, No. 5, May 1956, pp. 559-568.
Tiedt et al., "The Dynamies of the Coronary Venous Pressure in the Dog", Puugers Archiv 288, 27-42 (1966).
Muers et al., "The Reflex Cardiovascular Depression Caused by Occlusion of the Coronary Sinus in the Dog", J. Physiol. (1972), 221, pp. 259-282.
Arealis et al., "Arterialization of the Coronary Vein Coming from an Ischemic Area", Chest, vol. 63, No. 3, Mar. 1973.
Moll, "Revaskularisation des ischamischen Herzmuskels bei disseminierter Koronarsklerose", Zschr. Inn. Eds. Jahrg. 30(1975) Heft 1, pp. 10-14.
Lie et al., "Macroscopic Enzyme-Mapping Verification of Large, Homogeneous, Experimental Myocardial Infacts of Predictable Size and Location in Dogs", J. Thoracic and Cardiovascular Surgery, vol. 69, 1975, pp. 599-605.
Meerbaum et al., "Diastolic Retroperfusion of Acutely Ischemic Myocardium", The American Journal of Cardiology, vol. 37, 3/31/76, pp. 587-598.
Arealis et al., "Attempts to Increase Blood Supply to an Acutely Ischemic Area of the Myocardium by Intermittent Occlusion of the Coronary Sinus", Medical Research Engineering, 12(4), 1977, pp. 4-7.
Farcot et al., "Synchronized Retroperfusion of Coronary Veins for Circulatory Support of Jeopardized Ischemic Myocardium", The American Journal of Cardiology, vol. 41, Jun. 1978, pp. 11911201.
Farcot et al., "New Catheter-Pump System for Diastolic Synchronized Coronary Sinus Retroperfusion", Medical Progress through Technology, 8, pp. 29-37 (1980).
DeBoer et al., "Autoradiographic Method for Measuring the Ischemic Myocardium at Risk: Effects of Verapamil on Infarct Size After Experimental Coronary Artery Occlusion", Proc. Natl. Acad Sci. U.S.A., vol. 77, No. 10, pp. 6119 6123, Oct. 1980.
Mohl et al., "Effects of Intermittent Cornary Sinus Occlusion (ICSO) on Tissue Parameters After Ligation of LAD", 11th Europ. Conf. Microcirculation, Garmisch-Partenkirchen 1980 Biblthca anat., No. 20, pp. 517-520.
"Regional Coronary Blood Flow in Experimental Myocardial Ischemia", The American Journal of Cardiology, vol. 47, May 1981, pp. 1033-1040.
Glogar et al., "Pressure-Controlled Intermittent Coronary Sinus Occlusion Reduces Myocardial Necrosis", The American Journal of Cardiology, vol. 49 Mar. 1982.
Geary et al., "Quantitative Assessment of Infarct Size Reduction by Coronary Venous Retroperfusion in Baboons", The American Journal of Cardiology, vol. 50, Dec. 1982, pp. 1424-1430.
Gundry et al., "Modification of Myocardial Ischemia in Normal and Hypertrophied Hearts Utilizing Diastolic Retroperfusion of the Coronary Veins", J. Thora. Cardiovasc. Surg., vol. 83, No. 5, May 1982, pp. 659-669.
Sun et al., "Characterization of the Reactive Hyperemic Response Time During Intermittent Coronary Sinus Occlusion".
Mohl, "The Development and Rationale of Pressure-Controlled Intermittent Coronary Sinus Occlusion-A New Approach to Protect Ischemic Myocardium", Wiener Klinische Wochenschrift, vol. 96, No. 1, 1/6/84.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Heart analysis using pressure-controlled intermittent coronary s does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Heart analysis using pressure-controlled intermittent coronary s, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heart analysis using pressure-controlled intermittent coronary s will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-771272

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.