Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2003-02-26
2009-11-17
Horlick, Kenneth R. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200, C536S024330
Reexamination Certificate
active
07618773
ABSTRACT:
A method for the selective amplification of a target nucleic acid in a sample comprising the target nucleic acid and at least one non-target nucleic acid, the method comprising amplifying the nucleic acids by means of at least one oligonucleotide primer comprising:a primer region that can prime and extend on the target and non-target nucleic acids; anda region that is an inverted repeat of an internal sequence of an amplicon of the at least one non-target nucleic acid but which contains at least one mismatch to the corresponding internal sequence, if present, of an amplicon of the target nucleic acid.
REFERENCES:
patent: 5565340 (1996-10-01), Chenchik et al.
patent: 6326145 (2001-12-01), Whitcombe et al.
patent: 09-511149 (1997-11-01), None
patent: 96/23079 (1996-08-01), None
patent: 99/55905 (1999-11-01), None
patent: WO 99 55905 (1999-11-01), None
Bottema et al. Polymerase chain reaction amplification of specific alleles: A general method of detection of mutations, polymorphisms, and haplotypes. Methods in Enzymology (1993) 218: 388-402.
Brill et al. Differentiation between spore-forming and asporogenic bacteria using a PCR and Southern hybridization based method. Journal of Microbiological Methods. (1997) 31: 29-36.
Henke et al. Betaine improves the PCR amplification of GC-rich DNA sequences. Nucleic Acids Research. (1997) 25(19): 3957-3958.
Wilton et al. Snapback SSCP analysis: Engineered conformation changes for the rapid typing of known mutations. Human Mutation (1998) 11: 252-258.
Devon et al. Splinkerettes—improved vectorettes for greater efficiency in PCR walking. Nucleic Acids Research 23(9): 1644-1645 (1995).
Potaman, V.N. Prevention of Unexpectedly Long PCR Products Primed at Short Inverted Repeats. BioTechniques 27: 1110, 1112, and 1114 (1999).
International Search Report for PCT/AUO3/00244 dated May 21, 2003.
International Preliminary Examination Report for PCT.AUO3/00244 dated Jun. 2, 2004.
Supplemental European Search Report dated Sep. 24, 2007.
Natalia E. Broude, et al., “PCR based targeted genomic and cDNA differential display”, Genetic Analysis: Biomolecular Engineering, 1999, pp. 51-63, vol. 15.
James G. Herman, et al., “Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands”, Proc. Natl. Acad. Sci. USA, 1996, pp. 9821-9826, vol. 93.
I. A. Nazarenko, et al., “A closed tube format for amplification and detection of DNA based on energy transfer”, Nucleic Acids Research, 1997, pp. 2516-2521, vol. 25, No. 12.
Natalia E. Broude, “Stem-loop oligonucleotides: a robust tool for molecular biology and biotechnology”, Trends in Biotechnology, 2002, pp. 249-256, vol. 20, No. 6.
Natalia E. Broude et al., “PCR based targeted genomic and cDNA differential display”, Genetic Analysis: Biomolecular Engineering, vol. 15, pp. 51-63, 1999.
James G. Herman et al., “Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands”, Proc. Natl. Acad. Sci., vol. 93, pp. 9821-9826, 1996.
Molloy Peter Laurence
Rand Keith
Bertagna Angela
Commonwealth Scientific and Industrial Research Organisation
Horlick Kenneth R.
Sughrue & Mion, PLLC
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