HDV nucleic acid molecules and applications thereof

Details HDV nucleic acid molecules and applications thereof HDV nucleic acid molecules and applications thereof

2008-04-01

2008-04-01

Campell, Bruce R. (Department: 1648)

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

C530S826000, C530S820000, C530S806000, C424S185100, C424S186100, C424S189100

Reexamination Certificate

active

10489864

ABSTRACT:
The invention concerns nucleic acid molecules derived from novel hepatitis D virus strains or isolates constituting genotypes different from known I, II and III genotypes, their fragments, corresponding proteins and their uses as diagnostic reagents. The invention also concerns a method for sensitive diagnosis of the hepatitis D virus (or delta hepatitis virus) and a method for epidemiologic monitoring of HDV-related infections.

REFERENCES:
patent: 5932219 (1999-08-01), Houghton et al.
Chen et al. “Characterization and phylogenetic analysis of a novel hepatitis D virus strain discovered by restriction fragment length polymorphism analysis”. J. Gen Virology, vol. 79(1998), pp. 1105-1113.
Wu J-C et al “Characterization and phylogenetic analysis of a novel hepatitis D virus strain discovered by restriction fragment length polymorphism analysis” J Gen Virol. vol. 79 (1998) pp. 1105-1113.
Cotrina M et al “Hepatitis delta genotypes in chronic delta infection in the northeast of Spain (Catalonia)” J Hepatol. vol. 28 (1998), pp. 971-977.
Fumio Imazeki, et al., “Heterogeneity and evolution rates of delta virus RNA sequences”, Journal of Virology, vol. 64, No. 11, pp. 5594-5599 1990.
Database Genban 'en ligne! P. Deny: “Hepatitis delta virus genotypes I and II cocirculate in an endemic area of yakutia, Russia”, Database accession No. AJ309874 XP002196404 Abrege, Nov. 14, 2006.
Jaw-Ching Wu, et al. “Characterization and phylogenetic analysis of a novel hepatitis D virus strain discovered by restriction fragment length polymorphism analysis”, Journal of General Virology, vol. 79, pp. 1105-1113 1998.

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