HDAC inhibitor

Details HDAC inhibitor HDAC inhibitor

2006-11-14

2006-11-14

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S300000, C514S262100, C514S397000, C514S396000, C548S335100, C548S302700, C546S028000, C544S262000

Reexamination Certificate

active

07135493

ABSTRACT:
A compound having the following formula (I):whereinR1is N-containing heterocyclic ring optionally substituted with one or more suitable substituent(s),R2is hydroxyamino,R3is hydrogen or a suitable substituent,L1is —(CH2)n— (wherein n is an integer of 0 to 6) optionally substituted with one or more suitable substituent(s), wherein one or more methylene(s) may be replaced with suitable heteroatom(s), andL2is lower alkenylene,or a salt thereof. The compound is useful as a histone deacetylase inhibitor.

REFERENCES:
patent: WO 93/12075 (1993-06-01), None
patent: WO 95/13264 (1995-05-01), None
patent: WO 97/24117 (1997-07-01), None
patent: WO 01/38322 (2001-05-01), None
patent: WO 02/18326 (2002-03-01), None
patent: WO 02/22577 (2002-03-01), None
patent: WO 200222577 (2002-03-01), None
patent: WO 200224653 (2002-03-01), None
patent: WO 02/30872 (2002-04-01), None
patent: WO 02/074298 (2002-09-01), None
patent: WO 03/082288 (2003-10-01), None
patent: WO 03/087066 (2003-10-01), None

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