Drug – bio-affecting and body treating compositions – Lymphokine – Interferon
Reexamination Certificate
2005-02-01
2005-02-01
Andres, Janet L. (Department: 1646)
Drug, bio-affecting and body treating compositions
Lymphokine
Interferon
C424S085400, C514S042000, C514S458000, C514S474000
Reexamination Certificate
active
06849254
ABSTRACT:
Methods of treating patients having susceptible viral infections, especially chronic hepatitis C infection by administering to said patient a therapeutically effective amount of a combination therapy of interferon-alfa and ribavirin for a time sufficient to lower HCV-RNA in association with a therapeutically effective amount of an antioxidant for a time sufficient to ameliorate ribavirin-related hemolysis are disclosed.
REFERENCES:
patent: 4917888 (1990-04-01), Katre et al.
patent: 5951974 (1999-09-01), Gilbert et al.
patent: 6172046 (2001-01-01), Albrecht
patent: 6472373 (2002-10-01), Albrecht
patent: WO 9819670 (1998-05-01), None
Sies et al. Am. J. Clin Nutr., 1995, vol. 62, pp. 1315S-1321S.*
www.bayercare.com, One-A-Day 50 Plus and One-A-Day Antioxidant product sheets.*
Abella et al. Brit. J. Clin. Pharmacol., 1996, vol. 42, pp. 731-747.*
Brass, C.A., et al., “Do Antioxidants Ameliorate Ribavirin Related Anemia in HCV Patients”, Gastroenterology, (Apr., 1999) vol. 116, No. 4, Part 2, pp. A1192-A1193 (Mail date Mar. 24, 1999).
G.L. Davis, et al., N. Eng. J. Med., 1998, 339:1493-1499.
John G. McHutchinson, et al, N. Eng. J. Med., 1998, 339: 1485-1492.
T. Poynard, et al. , The Lancet, 1998, vol. 352, Oct. 31, pp. 1426-1432.
Reichard, et al., The Lancet, 1998; 351'83-87.
Shulman, Clinical Assessment of Hematologic Effects of Ribavirin in Humans, 1984, pp 79-92.
Brass Clifford A.
Glue Paul W.
Piken Edward
Andres Janet L.
Hoffman Thomas D.
Schering Corporation
Zaradic Sandy
LandOfFree
HCV combination therapy does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with HCV combination therapy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and HCV combination therapy will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3470604