HCMV-specific peptides, agents therefor and the use thereof

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence

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530326, 530327, 530328, 530345, C07K 402, C07K 14045, C07K 708

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active

058591850

ABSTRACT:
The invention relates to peptides for the immunochemical determination of human cytomegalovirus (HCMV)-specific antibodies and HCMV antigens, and to agents suitable for this method and to the use thereof.

REFERENCES:
Synthesis and Application of Acid Labile Anchor Groups for the Synthesis of Peptide Amides by Fmoc-solid-phase Peptide Synthesis, Breipohl et al., Int. J. Peptide Protein Res., 34: 262-267 (1989).
Mapping of Serologically Relevant Regions of Human Cytomegalovirus Phospho-protein p. 150 Using Synthetic Peptides, Novak et al., Journal of General Virology, 72: 1409-1413 (1991).
Map Position and Nucleotide Sequence of the Gene for the Large Structural Phosphoprotein of Human Cytomegalovirus, G. Jahn. et al., Journal of Virology, 61 (5): 1358-1367 (1987).
Hybridoma Technology in the Biosciences and Medicine, T.A. Springer, ed., Plenum Press NY, London, pp. 355-367 (1985).
Peroxidase-Labeled Antibody, A New Method of Conjugation, Nakane et al., J. of Histochem. and Cytochem., 22 (12): 1084-1091 (1974).
Enzyme-Labeling of Antibodies, Ishikawa et al., Journal of Immunoassay, 4 (3): 209-327 (1983).
Derwent Abstract for EP-A 0 268 014 A2.

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