Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.
Patent
1995-05-18
1998-04-14
Knode, Marian C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Glycoprotein, e.g., mucins, proteoglycans, etc.
435 693, 435 691, 435 697, 4241851, 4241921, 4242301, C12P 2106, C12P 2102, C07K 100, A61K 39245
Patent
active
057392927
ABSTRACT:
A fusion protein comprising a portion of a glycoprotein of HCMV fused to a portion of a glycoprotein of HSV is described.
REFERENCES:
Flexner, et al., "Successful vaccination with a polyvalent live vector despite existing immunity to an expressed antigen", Nature, 335, No. 6781, pp. 259-262 (1988).
Cranage, et al., "Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralizing antibodies via its expression in recombinant vaccinia virus", The Embo Journal, 5, No. 11, pp. 3057-3063 (1986).
Forrester, et al., "Construction and Properties of a Mutant of Herpes Simplex Virus Type 1 with Glycoprotein H Coding sequences Deleted", J. Virol., 66, No. 1, pp. 341-348 (1992).
Britt et al., J. Infect. Dis., 171:18-25, 1995.
Curtsinger et al., J. Gen. Virol., 75:301-307, 1994.
Eagle Alissa M.
Knode Marian C.
Lentz Edward T.
SmithKline Beecham Biologicals (S.A.)
Venetianer Stephen V.
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