Harmonic ultrasound imaging with microbubbles

Details Harmonic ultrasound imaging with microbubbles Harmonic ultrasound imaging with microbubbles

2008-05-20

2008-05-20

Padmanabhan, Sreeni (Department: 1617)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Ultrasound contrast agent

C424S009520, C600S453000

Reexamination Certificate

active

07374744

ABSTRACT:
A method for ultrasonic harmonic imaging is disclosed, which uses microbubbles particularly selected for their properties of reradiating ultrasound energy at frequencies other than the exciting frequency.

REFERENCES:
patent: 4265251 (1981-05-01), Tickner
patent: 4276885 (1981-07-01), Tickner et al.
patent: 4466442 (1984-08-01), Hilmann et al.
patent: 4613326 (1986-09-01), Szwarc
patent: 4657756 (1987-04-01), Rasot et al.
patent: 4664123 (1987-05-01), Iinuma
patent: 4684479 (1987-08-01), D'Arrigo
patent: 4718433 (1988-01-01), Feinstein
patent: 4774958 (1988-10-01), Feinstein
patent: 4832941 (1989-05-01), Berwing et al.
patent: 4844882 (1989-07-01), Widder et al.
patent: 4898734 (1990-02-01), Mathiowitz et al.
patent: 4904479 (1990-02-01), Illum
patent: 4925678 (1990-05-01), Ranney
patent: 4927623 (1990-05-01), Long, Jr.
patent: 4957656 (1990-09-01), Cerny et al.
patent: 5088499 (1992-02-01), Unger
patent: 5108759 (1992-04-01), Ranney
patent: 5123414 (1992-06-01), Unger
patent: 5141738 (1992-08-01), Rasor et al.
patent: 5149319 (1992-09-01), Unger
patent: 5155215 (1992-10-01), Ranney
patent: 5186922 (1993-02-01), Shell et al.
patent: 5190982 (1993-03-01), Erbel et al.
patent: 5195520 (1993-03-01), Schlief et al.
patent: 5196183 (1993-03-01), Yudelson et al.
patent: 5205287 (1993-04-01), Erbel et al.
patent: 5205290 (1993-04-01), Unger
patent: 5255683 (1993-10-01), Monaghan
patent: 5271928 (1993-12-01), Schneider et al.
patent: 5305757 (1994-04-01), Unger et al.
patent: 5310540 (1994-05-01), Giddey et al.
patent: 5315997 (1994-05-01), Widder et al.
patent: 5315998 (1994-05-01), Tachibana et al.
patent: 5333613 (1994-08-01), Tickner et al.
patent: 5334381 (1994-08-01), Unger
patent: 5348016 (1994-09-01), Unger et al.
patent: 5352435 (1994-10-01), Unger
patent: 5352436 (1994-10-01), Wheatley et al.
patent: 5376380 (1994-12-01), Kikuchi et al.
patent: 5380519 (1995-01-01), Schneider et al.
patent: 5393524 (1995-02-01), Quay
patent: 5409688 (1995-04-01), Quay
patent: 5410516 (1995-04-01), Uhlendorf et al.
patent: 5413774 (1995-05-01), Schneider et al.
patent: 5445813 (1995-08-01), Schneider et al.
patent: 5469854 (1995-11-01), Unger et al.
patent: 5540909 (1996-07-01), Schutt
patent: 5542935 (1996-08-01), Unger et al.
patent: 5552133 (1996-09-01), Lambert et al.
patent: 5556610 (1996-09-01), Yan et al.
patent: 5558094 (1996-09-01), Quay
patent: 5558853 (1996-09-01), Quay
patent: 5558854 (1996-09-01), Quay
patent: 5558855 (1996-09-01), Quay
patent: 5558856 (1996-09-01), Klaveness et al.
patent: 5558857 (1996-09-01), Klavenss et al.
patent: 5562893 (1996-10-01), Lohrmann
patent: 5580575 (1996-12-01), Unger et al.
patent: 5585112 (1996-12-01), Unger et al.
patent: 5639443 (1997-06-01), Schutt et al.
patent: 5678553 (1997-10-01), Uhlendorf et al.
patent: 5685310 (1997-11-01), Porter
patent: 5730954 (1998-03-01), Albayrak et al.
patent: 5733527 (1998-03-01), Schutt
patent: 5740128 (1998-04-01), Hossack et al.
patent: 6036644 (2000-03-01), Schutt
patent: 6056943 (2000-05-01), Schutt
patent: 3035189 (1989-08-01), None
patent: 663488 (1992-11-01), None
patent: 2002892 (1992-12-01), None
patent: 649996 (1994-06-01), None
patent: 652803 (1994-09-01), None
patent: 123235 (1984-10-01), None
patent: 131540 (1985-01-01), None
patent: 0230091 (1987-08-01), None
patent: 231091 (1987-08-01), None
patent: 0279379 (1988-08-01), None
patent: 586875 (1989-02-01), None
patent: 320433 (1989-06-01), None
patent: 0357164 (1990-03-01), None
patent: 0359246 (1990-03-01), None
patent: 0554213 (1993-08-01), None
patent: 606613 (1994-07-01), None
patent: 633030 (1994-07-01), None
patent: 0458745 (1994-09-01), None
patent: 5967229 (1984-04-01), None
patent: 8905160 (1989-06-01), None
patent: 9109629 (1991-07-01), None
patent: 9112823 (1991-09-01), None
patent: 9115999 (1991-10-01), None
patent: 9207250 (1992-04-01), None
patent: 9211873 (1992-07-01), None
patent: 9222247 (1992-12-01), None
patent: 9300930 (1993-01-01), None
patent: 9301712 (1993-02-01), None
patent: 9302712 (1993-02-01), None
patent: 9303671 (1993-03-01), None
patent: 9305819 (1993-04-01), None
patent: 9306869 (1993-04-01), None
patent: 9325242 (1993-12-01), None
patent: 9400422 (1994-01-01), None
patent: 9401140 (1994-01-01), None
patent: 9406477 (1994-03-01), None
patent: 9408707 (1994-04-01), None
patent: 9409703 (1994-05-01), None
patent: 9409829 (1994-05-01), None
patent: 9416738 (1994-08-01), None
patent: 9416739 (1994-08-01), None
patent: 9421175 (1994-09-01), None
patent: 9428797 (1994-12-01), None
patent: 9428939 (1994-12-01), None
patent: 9628090 (1996-09-01), None
Burns et al., Harmonic Imaging: New Imaging and Doppler Method for Contrast-enhanced US,Radiology, 1992.
Forsberg, et al., In Vivo Application of Contrast-enhanced Harmonic Imaging,Radiology, 1993.
Nanda, Meeting Report Second Biennial Scientific Congress of the International Society of Cardiovascular Ultrasound, World Congress on Echocardiography and Vascular Ultrasound, 1994.
Acoustic Non-Linearity Due to Micro-Bubbles in Water; Wesley & Safar,Acustica, 22: 177-182, 1969-70.
Ultrasonic Disruption; Alliger, Reprinted fromAmerican Laboratory, Oct. 1975.
Demonstration of Nonlinear Acoustical Effects at Biomedical Frequencies and Intensities; Carstensen, et al.,Ultrasound in Medicine&Biology, 6: 159-168, 1980.
Textbook of Diagnostic Ultrasonography, Second Edition, by Sandra Hagen-Ansert, pp. 10-12, 1983.
Application of the Ultrasonic Processors; Berliner, IIIBiotechnology Laboratory, 46-52, Mar. 1984.
Ultrasound Enhancement of Tissues During the Capillary Phase of PFOB—100% Immedicately Post Infusion; Mattrey, M.D., “Abstract, Association Of University Radiologists” 35thAnnual Meeting, Mar. 22-27, 1987.
Perflurochemicals as US Contrast Agents for Tumor Imaging and Hepatosplenography: Preliminary Clinical Results; Mattery, M.D., Radiology, 163: 339-343, 1987.
Perflurooctylbromide: A New Contrast Agent for CT, Sonography, and MR Imagining; Mattrey, M.D. Manuscript 1988.
Absorption and scatter of encapsulated gas filled microspheres: theoretical considerations and some measurements; de Jong, et al.,Ultrasonics, 30: No. 3, 95-103, 1992.
Simulated Capillary Blood Flow Measurement Using a Nonlinear Ultrasonic Contrast Agent, Schrope, et al.,Ultrasonic Imaging, 14: 134-158, 1992.
Liposomes, From Biophysics to Therapeutics, Edited by Mark J. Ostro, Marcel Dukker Inc., New York, pp. 2-8, 17-21,74 and 105.
Foundation of Colloid Science, vol. 1; Humter, et al., Clarendon Press, Oxford, pp. 20 & 22.
Peripheral Vascular Doppler Examinations; Rae, II,Textbook of diagnostic ultrasonsography, pp. 323-325.
“Principles and Recent Developments in Ultrasound Contrast Agents”; N. de Jong, et al.,Ultrasonics, 29:324-330, 1991.
“First Ultrasound Contrast Agent A waits OK from FDA”; Greer,Advance for Radiologic Science Professionals, pp. 3-5, 1993.
Kitagawa, et al.,Biological Abstracts63:6392 (1977).
Keough, et al.Biological Abstracts81: 105308 (1986).
Matsuda, et al. “Contrast Echocardiography of the Left Heaart by Intravenous Injection of Perfluorochemical Emulsion”J. of Cardiology13(4): 1021-1028 (1983).
Sunamotot, et al. “Liposomal Membranes”J. Biochem. 88:1219-1226 (1980).
Chapelon, et al. “Bubble Detection and Sizing with a Couble Frequency Doppler System”Ultrasonics26: 148-154 (1988).
Cathignol, et al. “Bubble Sizing with High Spatial Resolution” IEEE Transaction onUltrasonics, Ferroelectrics and Frequency Control 37(1): 30-37 (1990).
Miller, D.L. “Ultrasonic Detection of Resonant Cavitation Bubbles in a Flow tube by Their Second-Harmonic Emissions”Ultrasonics: 217-224 (1988).
Nakagawa. et al. “Imaging the Acoustic Nonlinearity Parameter with Finite-Amplitude Sound Waves . . . ”The Transactions of the IEICE71(8): 799-808 (1988).
Sandra Hagen-Ansert,Textbook of Diagnostic Ultrasonography, pp. 10-12 (2nded. 1983).
Marc J. Ostro,Liposomes From Biophysics to Therapeuticspp. 2-8; 17-21; 74 and 105 (1stEd. 1987).
I Robert J. Hunter,Foundations of Colloid

Affiliated with

Also associated with

Rating

Harmonic ultrasound imaging with microbubbles does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Harmonic ultrasound imaging with microbubbles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Harmonic ultrasound imaging with microbubbles will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2768815