Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical
Patent
1996-12-20
1999-01-19
Saucier, Sandra E.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Food or edible as carrier for pharmaceutical
426532, 426658, 426660, A61K 968, A23L 334, A23G 300
Patent
active
058611690
DESCRIPTION:
BRIEF SUMMARY
The invention relates to a candy known as a hard candy with tooth plaque-neutralizing effect, the use of a hard candy to clean the teeth, and a process and device for manufacturing a hard candy. The term hard candy is generally understood to mean oval compressed lozenges, chewable candies, pastilles, capsules, tablets, and similar presentations.
After the consumption of food and stimulants, tooth plaque is a particular risk due to the resulting acids. In particular, sugars cause and promote dental caries, and it is currently considered to be scientifically proven that carious lesions are the result of a process that affects hard tooth substances from the outside. The fermentation of orally administered carbohydrates into organic acids in bacterial tooth plaque and the related drop in the pH of that plaque are of primary importance for the formation of caries.
To neutralize tooth plaque acids, alkaline compounds, such as sodium carbonate, bicarbonate, and ammonium phosphate, as well as ureas, are recommended to counter the organic acids that are formed by the fermentation of carbohydrates. However, the salty and sometimes bitter taste of those buffers has made it difficult to use them.
The most effective mechanical method of inhibiting caries is to clean the teeth with toothpaste and a toothbrush after every occasion on which stimulants or food are consumed. However, it is not always possible to clean the teeth with toothpaste and a brush after every meal or every time food is consumed. That is particularly the case when away from home, traveling, at work, and the like.
EP-525 388 describes the manufacture and composition of a tablet having the aim of producing a slight foaming action to improve the taste of tablets containing active pharmaceutical ingredients, particularly calcium and magnesium. U.S. Pat. No. 4,409,202 describes a tablet or candy whose aim is to cover or neutralize mouth odor. The main active ingredient is a vegetable oil. U.S. Pat. No. 5,250,569 proposes the use of amino acids, including in connection with toothpastes, to avoid the unpleasant taste of orally-administered aluminum compounds. It would then be possible to produce special rhinitis medications containing aluminum. Another aim of that U.S. patent is to produce a slow-release effect for aluminum. The aim of JP-A-60237947 is the proprietary manufacture of a specific appearance for candy. A special look for the final product can be obtained by enclosing air bubbles, which are obviously intended to give the candy a refreshing effect. Finally, JP-A-62132815 suggests the manufacture of tablets to clean the mouth and deodorize the breath. However, both the state-of-the-art and proposed measures are not appropriate for effectively inhibiting caries.
Against that background, so-called plaque-neutralizing chewing gums have been available for some time that are intended both to stimulate the flow of saliva as a result of chewing movements and to contain the aforementioned active ingredients, which cause a buffer action in the saliva or result in neutralization of the acids produced during the fermentation of carbohydrates. Those chewing gums have the advantage that they can be used immediately after eating and can at least to a great extent neutralize the acids that damage the teeth. That may be done by stimulating the flow of saliva, whereby an increased buffer capacity is produced, by promoting the neutralization of plaque acids, by increasing the distribution of saliva in difficult to reach interdental spaces, by improved removal of food particles from the oral cavity, by creating a pH value that promotes remineralization of the tooth enamel, or finally by promoting remineralization by stimulating the flow of saliva with an increased mineral content.
Such chewing gums are also useful, for example, for patients with temporary or chronically limited mobility, which generally leads to poorer oral hygiene. In addition, when taking medications that inhibit the flow of saliva, the aforementioned chewing gum can be a useful tool for improving
REFERENCES:
patent: 3677770 (1972-07-01), Witzel
patent: 4048299 (1977-09-01), Litchfield et al.
patent: 4098914 (1978-07-01), Knechtel
patent: 4170632 (1979-10-01), Wagenknecht et al.
patent: 4303648 (1981-12-01), Witzel et al.
patent: 4409202 (1983-10-01), Witzel et al.
patent: 4568537 (1986-02-01), Hoermann et al.
patent: 5185153 (1993-02-01), Pollock
patent: 5250569 (1993-10-01), Godfrey
patent: 5312626 (1994-05-01), Gergely et al.
Derwent Publication Ltd., London, GB; AN 86-011915 & JP-A-60 237 947 (SAN EI CHEM IND KK), 26 Nov. 12985 see abstract and Patent Abstracts of Japan vol. 11 No. 361 (C-459) & JP, A, 62, 132815 (TANAKA KIICHI) 12 Jun. 1987, see abstract, both abstracts are taken from the International Search Report, which also is included herewith.
Patent Abstracts of Japan, vol. 11, No. 361, (C-459) , & JP,A, Jun. 16.
Derwent Publication, AN 86-011915, & JP-A-60 237, Nov. 26.
Dibona Holding AG
Saucier Sandra E.
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