Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adama

Details Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adama Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adama

1993-04-21

1995-06-13

Fleisher, Mindy B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

560102, C07H 2100, C07C 6976

Patent

active

054244145

ABSTRACT:
Novel tethered hapten intermediates and related conjugates based on 3- phenyl-1-adamantaneacetic acid, as well as methods for making and using such conjugates. Haptens based on the above core structure may be substituted at any position on the phenyl ring, especially at the para position. Using tethered intermediates, immunogens, tracers, solid supports and labeled oligonucleotides are all described; as are methods for using the intermediates to prepare the conjugates, methods of using the conjugates to make and purify anitbodies, as assay tracers, and in nucleic acid hybridization assays. Kits containing haptenated oligonucleotides and anti-hapten conjugates are also described.

REFERENCES:
patent: 3816509 (1974-06-01), Krimmel
patent: 4680275 (1987-07-01), Wagner et al.
McConnell, The Immune System, Blackwell Scientific, 1975, pp. 158-159.
Danifenko et al, Khim-ferm. Zh. 10(7) 60-62 (1976.
Kohler et al., Continuous Cultures of Fused Cells Secreting Antibody of Predefined Specificity, Nature, vol. 256, (Aug. 7, 1975) pp. 495-497.
Matthews et al., Analytical Strategies for the Use of DNA Probes, Analytical Biochemistry, vol. 169, (1988) pp. 1-25.
Fidanza et al., Use of a Thiol Tether for the Site-Specific Attachment of Reporter Groups to DNA, Journal of Organic Chemistry, vol. 57, (1992) pp. 2340-2346.

Affiliated with

Also associated with

Rating

Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adama does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adama, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adama will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1310215