Hapten-protein conjugates and methods of use in immunoassays

Details Hapten-protein conjugates and methods of use in immunoassays Hapten-protein conjugates and methods of use in immunoassays

1989-01-24

1991-02-05

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 14, 435 28, 435 792, 435961, 436543, 530350, 530402, 530403, 530405, C12Q 154, G01N 33535

Patent

active

049904434

ABSTRACT:
The present invention provides hapten derivatives of the general formula: ##STR1## wherein Hap is a residue formed from a hapten carrying a keto or aldehyde group by splitting off an oxo group and R.sup.1 and R.sup.2, which can be the same or different, are alkyl radicals containing up to 7 carbon atoms and one of the symbols R.sup.1 and R.sup.2 can also represent a hydrogen atom.
The present invention also provides hapten-protein conjugates of the general formula: ##STR2## wherein Hap, R.sup.1 and R.sup.2 have the above-given meanings and E--NH is the residue of a protein bound via an .epsilon.-amino group of a lysine residue.

REFERENCES:
Janoski et al.--Steroids, vol. 23 (1974), pp. 49-59.
Megges et al.--Chem. Abst. vol. 109 (1988), p. 93436d, original article, May, 1987.
Saltykova et al.--Chem. Abst. vol. 92 (1980), p. 198642b.
Yamauchi et al.--Chem. Abst. vol. 100 (1984), p. 49722j.
Janoski et al.--Chem. Abst. vol. 81 (1974), p. 35229f.
Zorina et al.--Chem. Abst. vol. 93 (1980), p. 46970q.

Affiliated with

Also associated with

Rating

Hapten-protein conjugates and methods of use in immunoassays does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hapten-protein conjugates and methods of use in immunoassays, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hapten-protein conjugates and methods of use in immunoassays will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-10114