Hapten-macromolecule conjugates useful in hapten assays

Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten

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436 8, 436822, 436547, 436548, 436815, 436518, 435967, 435 731, G01N 33531

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active

051660784

ABSTRACT:
The invention is a method for measuring a hapten poorly soluble in aqueous solution in a sample which includes the steps of reacting the hapten with an antibody specific for the hapten; and comparing the result of the reaction of the hapten and the antibody with the result of the reaction of the antibody and a water-soluble conjugate of the hapten and a water-soluble macromolecule having a molecular weight greater than about 1,000.

REFERENCES:
patent: 3322632 (1967-05-01), Schwick et al.
patent: 3514429 (1970-05-01), Stahmann et al.
patent: 4036823 (1977-07-01), Soares
patent: 4347312 (1982-08-01), Brown et al.
patent: 4410634 (1983-10-01), Cooper et al.
patent: 4530786 (1985-07-01), Dunbar et al.
patent: 4772551 (1988-09-01), Hart et al.
Voller "Heterogeneous Enzyme-Immunoassays and Their Applications" in Enzyme-Immunoassay, Maggio, Editor, pp. 181-196 (1980).
Furuya et al. "Gas-liquid chromatographic demonstration of the specificity of rabbit IgG antibody to the pesticide DDT and its metabolites", Mol. Immund. 18: 95-102 (1981).
The Merck Index pp. 125, 409-410, 27-28, 1018-1020 (1983).
Chu et al., J. Ass. Off. Anal. Chem. vol. 60, No. 4, "Preparation and Characterization of Aflatoxin B.sub.1 -1-(O-carboxymethyl) Oxime" pp. 791-794, 1977.
Chu et al., Appl. and Env. Micro., vol. 33, No. 5, "Production of Antibody Against Aflatoxin B.sub.1 " pp. 1125-1128, 1977.
Hammond, Chemical Abstracts, vol. 104(9), No. 65415z, 1985.
Experientia, vol. 35, No. 8, Aug. 1979, Basel CH pp. 1104-1107; W. O. Harder et al.: "Production and Characterization of Antibody Against Aflatoxin M1", p. 1106.
Chemical Abstracts, vol. 100, No. 1, Jan. 2, 1984, p. 389; col. 2; Ref. No. 4464K.
Chemical Abstracts, vol. 106, No. 25, Jun. 25, 1987, p. 190; col. 2; Ref. No. 208905p.

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