Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-06-07
1999-03-30
Marschel, Ardin H.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435442, 436501, 436530, 436532, 436543, 436 63, 436823, 536 221, 536 2532, C12Q 168, G01N 33566, C07H 1900, C07H 2100
Patent
active
058887288
ABSTRACT:
The present invention encompasses a capture membrane comprising a porous filter membrane having a hapten bound directly or indirectly to the membrane wherein complexes formed by specific binding having an anti-hapten bound to a binding member of the specifically binding complex are removed from a solution by the hapten as the solution passes through the membrane. In the preferred embodiment biotin is the hapten and avidin or streptavidin is the anti-hapten.
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Wilchek et al., "Review. The avidin-biotin complex in bioanalytical applications" Analytical Biochemistrry, vol. 171, pp. 1-32 1988.
Syvanen et al. "Fast quantification of nucleic acid hybrids by affinity-based hybrid collection" Nucleic Acids Research, vol. 14 No. 12, pp. 5037-5048, 1986.
Chelly et al. "Transcription of the dystrophin gene in human muscle and non-muscle tissues". Nature, vol. 333, pp. 858-860, 1988.
Armenta Richard D.
Burke Charles R.
Kung Viola T.
Olson John D.
Sheldon Edward L.
Marschel Ardin H.
Molecular Devices Corporation
Riley Jezia
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