Hapalindoles

Details Hapalindoles Hapalindoles

1986-02-14

1988-07-05

Ceperley, Mary E.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

435121, 435257, 548511, C07D20990, C07D20918

Patent

active

047556102

ABSTRACT:
New alkaloids called hapalindoles, which are antibacterial and antifungal agents, and methods of preparing these alkaloids by culturing the blue-green alga Hapalosiphon fontinalis ATCC 39694, are provided.

REFERENCES:
Biol. Abstr. 51:45694, abstracting O. P. Sachkova et al., "Problem on the Interspecies Antagonism of Cyanophyta Representatives," Vestn. Akad. nauk Kazakn. S.S.R. 25(5) 69-71.
M. R. Hagadone et al., "Defense Allomones of the Nudibranch Phyllidia varicosa Lamarck 1801," Helv. Chim. Acta 62(7) 2484-2494 (1979).
M. Nobuhara et al., "A Fungal Metabolite, Novel Isocyano Expoxide," Chem. Pharm. Bull 24(4), 832-834 (1976).
H. Achenbach et al., "Zur Biogenese des Xanthocillins," Z. Naturforsch B. 20, 137 (1965).
Chem. Abstr.: 6362c (1958), abstracting I. Hagedorn et al., "Clarifying the Constitution of Xanthocillin," Pharmazie 12, 567-580 (1957).
D. Brewer et al., "Isonitrile Acids from Cultures of the Fungus Trichoderma hamatum (Bon.) Bain. aggr., X-Ray Structure," J.C.S. Chem. Comm. 1979, 1061-1062.
J. Tsaklidis et al., Chem. Abstr. 87:84758k (1977).
P. N. Srivastava, "Taxonomy and Biology of Blue-Green Alga" T. V. Desikachary, ed., U. Madras, 1972, pp. 391-392.
R. Moore et al, J. Am. Chem. Soc. (1984), 106, 6456-6457.

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