Hand-held inhalation-actuated spray device

Surgery – Liquid medicament atomizer or sprayer – Pre-pressurized container holding medicament

Patent

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Details

12820014, 12820312, 12820523, A61M 1100

Patent

active

056924925

DESCRIPTION:

BRIEF SUMMARY
BACKGROUND OF THE INVENTION

The present invention relates to a hand-held inhalation-actuated spray device, and more particularly to a spray device whereby a dose of medicine is sprayed into the respiratory tract of a patient synchronously with said patient breathing in.
Numerous mechanical devices of this type are known which comprise: position and an actuated position, said dispenser device issuing a measured amount of said substance when the actuator member is displaced from its rest position to its actuated position, said actuator member being urged resiliently towards its rest position, the dispenser device also having an outlet for issuing said substance; communicates with said outlet for said substance; actuated position; actuator member urging means, and a released position in which it no longer locks said urging means; and position while suction is being applied to said inhale duct.
In purely mechanical devices, the means for unlocking the locking mechanism generally include a flap that is displaceable by the patient inhaling. The examples of such devices are given in the following documents: U.S. Pat. No. 3,456,645, U.S. Pat. No. 3,456,646, U.S. Pat. No. 3,598,294, U.S. Pat. No. 3,605,738, U.S. Pat. No. 3,636,949, U.S. Pat. No. 3,732,864, U.S. Pat. No. 3,789,843, U.S. Pat. No. 3,814,297, GB-A-1 392 192, CH-A-511 063, FR-A-2 615 106, FR-A-2 658 081, EP-A-0 147 028 (and corresponding patent U.S. Pat. No. 4,664,107), EP-A-0 414 536, EP-A-0 428 380, EP-A-0 045 419, DE-A-30 40641, DE-A-40 15367, and DE-U-89 12098.
Those purely mechanical devices suffer from the drawback that the energy required for passing the locking mechanism from its locked state to its unlocked state is provided solely by the patient breathing in, so they therefore require the patient to breath quite hard. In such systems, it is very difficult to minimize the energy that the patient must provide in order to pass the locking system from its locked state to its unlocked state since that could cause untimely operation of the device. Unfortunately, such devices need to be used even by people who are incapable of breathing in hard, such as children, old people, sufferers of asthma, people who are weak, etc. . . . .
In addition, in prior art devices, the amount of suction required to trigger spraying depends on friction between mechanical parts, and it is known that such friction is very difficult to control, and that it varies depending on the amount of wear. Such systems are therefore relatively inaccurate as to the amount of suction required to trigger spraying.


SUMMARY OF THE INVENTION

An object of the present invention is to eliminate the above drawbacks.
The present invention thus provides a device of the above-mentioned type, comprising: purpose of controlling it; circuit on detecting suction in the inhale duct, the electronic control circuit then causing the electrical actuator to displace the latch member into its released position; sensor for detecting proper orientation of said device, in which said position sensor is connected to said electronic control circuit, and said electronic control circuit is adapted to trigger actuation of the device only in the event of said position sensor detecting that the device is in said proper orientation.
Advantageously, said suction sensor measures suction in said inhale duct relative to atmospheric pressure, and delivers a signal representative of the suction to the electronic control circuit.
A technical problem encountered with sprays that are triggered by inhalation is that the suction created by the patient in the inhale duct varies depending on the patient. Thus, for a patient who does not breathe in hard, spraying may be triggered much too late in the breathing cycle, and may even not be triggered at all.
In an embodiment of the invention, this problem is solved in that said position sensor includes means for detecting a particular position of the device and for causing said electronic control circuit to operate in a calibration mode, in which case the device is not actuated when

REFERENCES:
patent: 4109656 (1978-08-01), Goethel et al.
patent: 4198626 (1980-04-01), Rauscher
patent: 4414972 (1983-11-01), Young et al.
patent: 4648393 (1987-03-01), Landis et al.
patent: 5069204 (1991-12-01), Smith et al.
patent: 5284133 (1994-02-01), Burns et al.
patent: 5347998 (1994-09-01), Hodson et al.
patent: 5363842 (1994-11-01), Mishelevich et al.
patent: 5452711 (1995-09-01), Gault
patent: 5497764 (1996-03-01), Ritson et al.
patent: 5507277 (1996-04-01), Rubsamen et al.

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