Hand-held aerosol dispenser for therapeutic liquids

Fluid sprinkling – spraying – and diffusing – Including supply holder for material – And frangible seal rupturing means

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Details

239338, 239370, 239127, 12820011, 12820018, 12820021, 12820321, A61M 1108, A61M 1500

Patent

active

054906300

DESCRIPTION:

BRIEF SUMMARY
BACKGROUND OF THE INVENTION

The invention relates to a hand-held aerosol dispenser, and more particularly a hand-held aerosol dispenser for a therapeutic liquid used in inhalation therapy.
A hand-held aerosol dispenser for automizing therapeutic liquid, which is held by hand by patients for treatment at home is disclosed, for example, in the German Utility Patent 90 11 768. In the device according to the prior art, a reservoir for the liquid to be atomized is an integral part of the housing. Until now, the patient prepared for the inhalation by mixing an amount of medication and water required for one or several inhalations. The mixture was then transferred to the aerosol dispenser, after which the patient commenced with the inhalation.
Especially with asthmatics suffering an acute attack, this time-consuming preliminary work is beset by the problem that because of the sudden respiratory distress that increases rapidly, the patient panics and, as a result, is often not in a position to carry out the preparations for the necessary inhalation.
As an alternative treatment, an emergency powder inhalation may be used by the asthmatic. However, as a rule, only a medication of a related type is available. Moreover, the dry powder inhalation in most cases exerts a strongly irritating effect on the already damaged bronchia.
Furthermore, simple tap water has been used in the prior art, for moistening the bronchial region as well as for preparing a mixture of water and the drug. Such water may prove unsuitable for inhalation therapy. Although there are usually no complications when such water is used for external and oral applications, the impurities contained in tap water can, in certain instances, lead to serious infections in the lung.
U.S. Pat. No. 3,915,386 discloses a room humidifier, which also works with an atomizing nozzle. Such room humidifiers are used for the purpose of optimizing the room atmosphere in sensitive areas, such as in operating rooms. The known humidifier has a reservoir, which can be screwed into the housing from below and can contain sterilized water. The known apparatus is not suitable for use as a hand-held device, because the reservoir has a capacity of about 1 liter and is also not intended for atomizing a drug mixture, since such use would be inappropriate for room humidification.


OBJECTS AND SUMMARY OF THE INVENTION

It is therefore an object of the invention to develop a hand-held aerosol dispenser of the aforementioned type further, which is ready for use at all times and for which the use of contaminated water is precluded.
Briefly stated, there is provided a hand-held aerosol dispenser available, with which sterile water or a mixture of sterile water and a drug are supplied in a reservoir, which can be removed from the housing. The patient can mix the amount of the drug prescribed by the doctor with the sterile water, in the reservoir. When the reservoir is coupled with the housing, the hand-held aerosol dispenser is ready for use for about 20 inhalations, which normally corresponds to 7 days. Due to the absence of nutrients in the sterile water, the body's own bacteria, which subsequently reach the sterile water through the top of the reservoir, cannot adversely affect the liquid held therein.
In a further embodiment of the present invention, an already pre-mixed drug is pre-filled within the reservoir, so that the patient need only connect the reservoir with the housing, in order to obtain an aerosol dispenser that is ready for use.
A suction nozzle, through which the therapeutic liquid is drawn, and which reaches almost to the bottom of the reservoir, ensures that the reservoir can be emptied almost completely.
According to a further feature of the invention, improved atomizing results and, moreover, particularly with respect to the separation of the small droplets from the larger ones, is achieved by surrounding the atomizing nozzle with a cylindrical separation chamber, which is open at the bottom and disposed within the housing a distance from its side. The separating cha

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