Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1986-06-02
1988-08-09
Hollrah, Glennon H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
544182, 544194, 544211, 544213, 544224, 544238, 544239, 544240, 544241, 544317, 544320, 544321, 544322, 544327, 544330, 544331, 544332, 544408, 544409, 546146, 546159, 546297, 546306, 548128, 548130, 548132, 548133, 548183, 548184, 548186, 548189, 548191, 548193, 514361, 514369, 514370, C07D27704, C07D28508
Patent
active
047629320
ABSTRACT:
Compounds useful for inhibiting gastric acid secretion and for the treatment of peptic ulcers caused or exacerbated by gastric acidity having the following formula (I): ##STR1## in which R.sup.1 and R.sup.2, are H, C.sub.1-10 alkyl, C.sub.3-8 cycloalkyl or cycloalkylalkyl in which the alkyl part is C.sub.1-6 and the cycloalkyl part is C.sub.3-8, each of the alkyl, cycloalkyl and cycloalkylalkyls being optionally substituted by one or more halogens selected from F, Cl and Br, provided that at least one of R.sup.1 and R.sup.2 is a halogen substituted alkyl, cycloalkyl or cycloalkylalkyl and provided that there is no halogen substituent on the carbon directly attached to the nitrogen; and X, m, Y, n and R.sup.3 are as described in the specification; and the pharmaceutically-acceptable acid-addition salts thereof. Processes for producing compounds of formula (I), pharmaceutical compositions containing them, methods of utilizing such compositions and intermediates useful for synthesizing compounds of formula (I) are also described.
REFERENCES:
patent: 4451463 (1984-05-01), Large
patent: 4496571 (1985-01-01), Yellin et al.
patent: 4562261 (1985-12-01), Hirata et al.
Edwards Philip N.
Large Michael S.
Yellin Tobias O.
Hollrah Glennon H.
ICI Americas Inc.
Imperial Chemical Industries Ltd.
Turnipseed James H.
LandOfFree
Haloguanidine intermediates does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Haloguanidine intermediates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Haloguanidine intermediates will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-919523