Halogenation of pyridine compounds

Details Halogenation of pyridine compounds Halogenation of pyridine compounds

1980-01-16

1981-03-31

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546346, C07D21326

Patent

active

042594960

ABSTRACT:
Side-chain fluorination of 3-methylpyridine is carried out by reaction with hydrogen fluoride and chlorine in the liquid phase. The main products are 3-trifluoromethylpyridine, 3-chlorodifluoropyridine and 3-difluoromethylpyridine.

REFERENCES:
patent: 4031100 (1977-06-01), Giacobbe
patent: 4071521 (1978-01-01), Muench
patent: 4101554 (1978-07-01), Tobin

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