Halogenating reagents

Chemistry of carbon compounds – Dipeptides – e.g. – aspartame – anserine – carnosine – etc.

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260986, 544 16, 544 30, C07F 914

Patent

active

042306442

ABSTRACT:
Novel halogenating agents are derived from triaryl phosphites and chlorine or bromine. They are useful in converting 7-acylamino-3-hydroxy-3-cephem compounds to 7-acylamino-3-halo-3-cephems and the corresponding C-7 imino halide cephem derivatives.

REFERENCES:
Harris et al., "J. Chem. Soci.", (1956), 3038.
Foroman et al., "J. Am. Chem. Soci.", vol. 75, (1953) p. 3145.
Ramirez et al., "J. Am. Chem. Soci.", vol. 90, (1968) p. 3507.
Milobedzki et al., "Rocznik Chemie," vol. 6, (1926) p. 67.
Coe et al., "J. Chem. Soci.", (London), pp. 2281-2288, (1954).
Rydon et al., "J. Chem. Soci.", (London), pp. 3043-3056, (1956).

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