Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-08-23
2008-08-26
Desai, Rita J (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C549S297000
Reexamination Certificate
active
07417069
ABSTRACT:
Compounds having the structure I:are useful for inducing cell death (apoptosis) and in immunosuppression. In structure I,CR1R2is selected from CHOH, C═O, CHF, CF2and C(CF3)OH;CR6and CR13are selected from CH, COH and CF;CR7R8, CR9R10and CR11R12are selected from CH2, CHOH, C═O, CHF and CF2; andCR3R4R5is selected from CH3, CH2OH, C═O, COOH, CH2F, CHF2and CF3;such that: at least one of R1-R13comprises fluorine;no more than two of CR3R4R5, CR6, CR7R8, CR9R10, CR11R12, and CR13comprises fluorine or oxygen;and, when CR1R2is CHOH, CR3R4R5is not CH2F.
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Dai Dongcheng
Musser John H.
Dehlinger Peter J.
Desai Rita J
Evans Susan T.
Gorthey LeeAnn
Pharmagenesis, Inc.
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