Halogen substituted carbamate compounds from 2-phenyl-1,2-ethane

Details Halogen substituted carbamate compounds from 2-phenyl-1,2-ethane Halogen substituted carbamate compounds from 2-phenyl-1,2-ethane

1996-01-16

1997-12-16

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

N-c doai

560164, 514489, A61K 3127

Patent

active

056985886

ABSTRACT:
The pure enantiomeric forms, as well as enantiomeric mixtures excluding the racemic mixture of monocarbamates of 2-phenyl-1,2-ethanediol substituted with more than one halogen atom on the phenyl ring and dicarbamates of 2-phenyl-1,2-ethanediol substituted with more than one halogen atom on the phenyl ring have been found to be effective in the treatment of disorders of the central nervous system.

REFERENCES:
patent: 2884444 (1959-04-01), Berger
patent: 2937119 (1960-05-01), Berger et al.
patent: 3144389 (1964-08-01), Bossinger
patent: 3248418 (1966-04-01), Bossinger
patent: 3265727 (1966-08-01), Bossinger
patent: 3265728 (1966-08-01), Bossing et al.
patent: 3313692 (1967-04-01), Bossinger
patent: 3313696 (1967-04-01), Bossinger
patent: 3313697 (1967-04-01), Bossinger
patent: 3313699 (1967-04-01), Bossinger
patent: 3313700 (1967-04-01), Bossinger
patent: 3509162 (1970-04-01), Bsendorfetal
Bergen, "J. Pharm. Exp. Ther." 104, 229-233 (1952).
DeSala et al. "Toxicology and Applied Pharmacology", 2, 397-402 (1960).

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