Halogen derivatives of clavulaic acid

Details Halogen derivatives of clavulaic acid Halogen derivatives of clavulaic acid

1976-12-10

1980-10-28

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

546272, E07D49804

Patent

active

042306221

ABSTRACT:
Novel halogen derivatives of clavulanic acid are described which are of value in the preparation of a range of clavulins which either inhibit .beta.-lactamases or show activity against strains of both gram-positive and gram-negative bacteria. Processes for preparing the halogen derivatives are described and methods for converting them into the active clavulins are given.

REFERENCES:
Cram et al. "Organic Chemistry" 2nd Ed., McGraw-Hill, N.Y. (1964) pp. 258-259.

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