Halogen derivatives of 8-hydroxycarboxylic acids; the processes

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic or structurally-modified peptidoglycan or...

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2603435, 260465D, 562470, 424317, A61K 31335, C07D30930, C07C 5911

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active

042872065

ABSTRACT:
Halogen derivatives of 8-hydroxycarboxylic acids, which correspond to the formula ##STR1## (open form, in a basic medium) or to the formula ##STR2## (cyclized form, in an acid medium) in which formulae: X.sub.1 and X.sub.2 are halogen atoms, n.sub.1 and n.sub.2 are integers between 0 and 5, but, if n.sub.1 =0, n.sub.2 is different from 0, and vice versa, R is a hydrogen atom or an alkyl or aryl group, and Cation represents an ion originating from a base, or a metal ion, which is pharmaceutically compatible are suitable as antidepressants having a psychostimulant action.

REFERENCES:
patent: 4113742 (1978-09-01), Simon
patent: 4163799 (1979-08-01), Simon
patent: 4198425 (1980-04-01), Mitsui et al.

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