Haloarylmalonamidooxacephalosporins

Details Haloarylmalonamidooxacephalosporins Haloarylmalonamidooxacephalosporins

1978-04-26

1980-01-15

Randolph, John D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 90, C07D41302, A61K 31395, A61K 31535

Patent

active

041839285

ABSTRACT:
Antibacterial haloarylmalonamido-1-dethia-1-oxacephalosporins of the following formula: ##STR1## wherein Ar is ##STR2## (in which Hal and Hal' each is halogen and RO is hydroxy or protected hydroxy);

REFERENCES:
patent: 4013653 (1977-03-01), Wolfe
patent: 4045438 (1977-08-01), Haviv et al.
patent: 4048311 (1977-09-01), Berges
Lednicer et al., The Organic Chemistry of Drug Synthesis, pp. 416-421, John Wiley and Sons, 1977.
Firestone et al., J. Med. Chem., vol. 20, pp. 551-556, Apr. 1977.

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