Halo-nitro-isoquinolinone compounds and pharmaceutical compositi

Details Halo-nitro-isoquinolinone compounds and pharmaceutical compositi Halo-nitro-isoquinolinone compounds and pharmaceutical compositi

1995-06-06

1997-07-29

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546142, C07D21724, C07D21722, A61K 3147

Patent

active

056523670

ABSTRACT:
Unsubstituted or substituted halo nitro and nitroso compounds and their metabolites are potent, selective and non-toxic inhibitors and supressants of cancer growth and vital infections in a mammalian host. The compounds are particularly useful for treatment and supression of tumors and viruses associated with breast cancer, AIDS, herpetic episodes and cytomegaloviral infections. The methods of treatment of tumorigenic and vital diseases by halo nitro and nitroso compounds and their metabolites are described.

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