Hairpin ribozymes

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives


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4353201, 435325, 435354, C07H 2104, C12N 506, C12N 1563




Hairpin ribozyme lacking a substrate moiety, comprising at least six bases in helix 2 and able to base-pair with a separate substrate RNA, wherein the said ribozyme comprises one or more bases 3' of helix 3 able to base-pair with the said substrate RNA to form a helix 5 and wherein the said ribozyme can cleave and/or ligate said separate RNA(s) in trans.

patent: 5334711 (1994-08-01), Sproat et al.
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