Hairless mouse sensitive to helicobacter pylori

Details Hairless mouse sensitive to helicobacter pylori Hairless mouse sensitive to helicobacter pylori

1998-03-25

2000-03-21

Chambers, Jasemine C.

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

800 9, A01K 6700

Patent

active

060404957

ABSTRACT:
A hairless mouse designated NS:Hr/ICR is sensitive to H. pylori. This NS:Hr/ICR hairless mouse can be easily infected with H. pylori in its alimentary canal, and is therefore useful as an experimental animal model for H. pylori infection.

REFERENCES:
patent: 5602304 (1997-02-01), Suzuki et al.
Mikio Karita, et al., The American Journal of Gastroenterology, vol. 89, No. 2, pp. 208 to 213, "Establishment of a Small Animal Model for Human Helicobacter pylori Infection Using Germ-Free Mouse", 1994.
Jerroid M. Ward, et al., Laboratory Animal Science, vol. 46, No. 1, pp. 15 to 20, "Inflammatory Large Bowel Disease in Immunodeficient Mice Naturally Infected with Helicobacter hepaticus", Feb. 1996.
P. Ghiara, et al., vol. 37, No. 01, p. 201, "Infected by Helicobacter pylori in a Mouse Model That Mimics Human Disease: Protection by Oral Vaccination", Jul. 7, 1995.
A. A. McColm, et al., vol. 41, No. 1, p. a122, "The Importance of the Challenge Inoculum in Colonisation of HSD/ICR Mice with H. Pylori", Sep. 1997.
R. L. Ferrero, et al., vol. 41, No. 1, p. a122, Colonisation of Mice by H. Pylori SS1; Similarities with an Acute Infection in Man, Sep. 11, 1997.
Unidentified Curved Bacilli on Gastric Epithelium in Active Chronic Gastritis, The Lancet, Jun. 4, 1983, p. 1273-75.
Yokota K. et al., Colonization of Helicobacter pylori in the Gastric Mucosa of Mongolian Gerbils, Microbiol. Immunol. vol. 35(6), 475, 1991.
Marchetti, M., et al., Development of a Mouse Model of Helicobacter pylori Infection That Mimics Human Disease, Science, vol. 267, Mar. 17, 1995, 1655-1658.
Smith et al. Clinical and Diagnostic Laboratory Immunology, vol. 3, pp. 66-72, Jan. 1996.
Karita et al. The American Journal of Gastroenterology, vol. 89, pp. 208-213, Feb. 1994.

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