Haemostatically active preparation containing vWF and method...

Details Haemostatically active preparation containing vWF and method... Haemostatically active preparation containing vWF and method...

2007-01-23

2007-01-23

Weber, Jon (Department: 1653)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Separation or purification

C530S383000, C530S384000

Reexamination Certificate

active

10257375

ABSTRACT:
A process for preparing a hemostatically active preparation containing von Willebrand factor (vWF) from a fraction of human plasma by chromatographic purification of a vWF-containing plasma fraction on an anion-exchange material which has the anion-exchanging groups on grafted polymeric structures (tentacle materials), collecting a vWF-containing fraction, followed by purification of said fraction using gel permeation to prepare a purified thermally stable vWF-containing preparation; and heating the preparation for inactivating viruses.

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patent: WO 93/15105 (1993-08-01), None
Mazurier et al., “Developement preclinique du concentre de facteur Willebrand vWF SD-35-dh”, Sang Thrombose Vaisseaux, vol. 11, No. Spezial, (Oct. 1999), XP-000925923, pp. 30-35.

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