Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Reexamination Certificate
2008-07-01
2008-07-01
Campell, Bruce (Department: 1648)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
C424S130100, C424S141100, C424S232100, C424S184100
Reexamination Certificate
active
07393533
ABSTRACT:
The invention relates to, among other things, methods of protecting against poxvirus infection or pathogenesis and including pox viruses such as small pox (variola major and variola minor), cowpox, monkey pox vaccinia virus, and Molluscum Contagiosum using compositions such as human, humanized and chimeric antibodies that specifically bind to H3L protein.
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patent: 2006/0062800 (2006-03-01), Cohen et al.
patent: 03/068151 (2003-08-01), None
Patt H. and Feigin R., Diagnosis and Management of Suspected Cases of Bioterrorism: A Pediatric Perspective, 2002, Pediatrics, vol. 109, No. 4, pp. 685-692.
Aldaz-Carroll et al., Epitiope-Mapping Studies Define Two Major Neutralization Sites on the Vaccinia Virus Extracellular Enveloped Virus Glycoprotein B5R, 2005, Journal of Virology, vol. 79, No. 10, pp. 6260-6271.
Boulanger, D., et al., Identification and Characterization of Three Immunodominant Structural Proteins of Fowlpox Virus, J. of Virology, 76(19):9844-9855 (2002).
da Fonseca, F.G., et al., Characterization of the Vaccinia Virus H3L Envelope Protein: Topology and Posttranslational Membrane Insertion via the C-Terminal Hydrophobic Tail, J. of Virology, 74(16):7508-7517 (2000).
da Fonseca, F.G., et al., Effects of Deletion or Stringent Repression to the H3L Envelope Gene on Vaccinia Virus Replication, J. of Virology, 74(16):7518-7528 (2000).
Pedersen, K., et al., Characterization of Vaccinia Virus Intracellular Cores: Implications for Viral Uncoating and Core Structure, J. of Virology, 74(8):3525-3536 (2000).
Crotty Shane
Davies David Huw
Felgner Philip L
Blumel Benjamin P
Campell Bruce
La Jolla Institute for Allergy and Immunology
Pillsbury Winthrop Shaw & Pittman LLP
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