H2N3 influenza A viruses and methods of use

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S320100

Reexamination Certificate

active

08084594

ABSTRACT:
The present invention provides influenza A viruses that include a hemagglutinin subtype H2, a neuraminidase subtype N3, or the combination thereof. Included in the present invention are H2 hemagglutinins and N3 neuraminidases, and the polynucleotides encoding the polypeptides. Antibody to the polypeptides, and methods of using the viruses, polypeptides, polynucleotides, and antibodies are also provided.

REFERENCES:
Naeve “Fatty acids on the A/Japan/305/57 influenza virus hemagglutinin have a role in membrane fusion” EMBO J. 3857-3866;1990.
Obenauer, J. C. et al. “Large-Scale Sequence Analysis of Avian Influenza Isolates” Science 311:1576-1580; 2006.
Obenauer, J.C. et al. “Supporting Online Material for Large-Scale Sequence Analysis of Avian Influenza Isolates” Published Jan. 26, 2006 on Science Express. Page numbers are not identified.

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