H2-M modified transgenic mice

Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – Transgenic nonhuman animal

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800 21, 800 22, 800 25, 800 11, 800 3, 435455, 435463, 4353201, 435325, 435 691, 435 912, 435 4, 424 921, C12N 1509, C12N 1563, C12N 1500, C12N 500

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active

060020660

ABSTRACT:
A transgenic mouse with alterations in the H2-Ma gene is prepared by introduction of an altered H2-Ma gene into a host mouse. The resulting transgenic mice do not produce functional H2-M molecules.

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Antigen Presentation and T Cell Development in H2-M-Deficient Mice, Wai-Ping Fung-Leung, Science, vol. 271, 1278-1281, Mar. 1,1996.

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