Gyrase inhibitors and uses thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S221000, C514S227800, C514S234500, C514S255030, C514S256000, C514S269000, C514S318000, C514S394000, C540S229000, C544S081000, C544S124000, C544S132000, C544S280000, C544S281000, C544S282000, C544S319000, C544S370000, C544S380000, C546S193000, C546S273400, C548S302700, C548S304400

Reexamination Certificate

active

07495014

ABSTRACT:
The present invention relates to compounds which inhibit bacterial gyrase and/or Topo IV and pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infection. Accordingly, the present invention also relates to methods for treating bacterial infections in mammals.

REFERENCES:
patent: 3856957 (1974-12-01), Seng et al.
patent: 6632809 (2003-10-01), Grillot et al.
patent: 2004/0043989 (2004-03-01), Grillot et al.
patent: 2005/0038247 (2005-02-01), Charifson et al.
patent: 2005/0256136 (2005-11-01), Charifson et al.
patent: 2006/0025424 (2006-02-01), Charifson et al.
patent: WO 02/060879 (2002-08-01), None
patent: WO 03/105846 (2003-12-01), None
Eckert et al. “The antifungal activity of . . . ” CA 93:39290 (1980).
MayoClinic “Antibiotic associated diarrhea” Mayoclinic.com. (2007).
Wassenaar “Bacteria;more than pathogens” Am. Ins. biol. Sci. internet p. 1-7 (2002).
Webster's Dictionary (1984) p. 933.
Kus et al., “Synthesis and Antimicrobial Activities of 5-fluoro-1,2,6-trisubstituted Benzimidazole Carboxamide and Acetamide Derivatives” Arch. Pharm. Pharm. Med. Chem., vol. 334, No. 11, pp. 361-365, 2001.
Sun et al., “Synthesis and Evaluation of Terbenzimidazoles as Topoisomerase I Inhibitors” J. Med. Chem., vol. 38, No. 18, pp. 3638-3644, 1995.
Hubschwerlen et al., “Pyrimido[1,6-a]benzimidazoles: A New Class of DNA Gyrase Inhibitors” J. Med. Chem, vol. 35, No. 8, pp. 1385-1392, 1992.
Office Action mailed Aug. 26, 2005 for U.S. Appl. No. 10/833,995.
Office Action mailed Mar. 17, 2006 for U.S. Appl. No. 10/833,995.
Office Action mailed Mar. 15, 2007 for U.S. Appl. No. 10/833,995.
Office Action mailed Sep. 14, 2006 for U.S. Appl. No. 10/833,995.
Office Action mailed Mar. 25, 2005 for U.S. Appl. No. 10/833,995.
Office Action mailed Jun. 16, 2006 for U.S. Appl. No. 10/444,588.
Office Action mailed Mar. 21, 2007 for U.S. Appl. No. 10/444,588.
Office Action mailed Aug. 10, 2006 for U.S. Appl. No. 10/459,420.
Office Action mailed May 3, 2007 for U.S. Appl. No. 10/459,420.
Office Action mailed Dec. 28, 2007 for U.S. Appl. No. 10/459,420.
Office Action mailed Nov. 5, 2007 for U.S. Appl. No. 10/901,928.
Office Action mailed Dec. 21, 2007 for U.S. Appl. No. 10/971,573.
Office Action mailed Dec. 3, 2007 for U.S. Appl. No. 10/986,569.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Gyrase inhibitors and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gyrase inhibitors and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gyrase inhibitors and uses thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4138412

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.