Gyrase inhibitors and uses thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reissue Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S234500, C514S252140, C514S252190, C514S256000, C514S269000, C514S275000, C514S293000, C514S303000, C514S314000, C514S318000, C514S322000, C514S338000, C514S364000, C514S375000, C514S395000, C540S578000, C544S122000, C544S124000, C544S324000, C544S330000, C544S331000, C544S333000, C546S082000, C546S118000, C546S167000, C546S193000, C546S199000, C546S271700, C546S273100, C546S273400, C548S143000, C548S222000, C548S304700, C548S305100, C548S308100

Reissue Patent

active

RE040245

ABSTRACT:
The present invention relates to compounds of the formula I:or a pharmaceutically acceptable derivative or prodrug thereof. The compounds are useful as inhibitors of bacterial gyrase activity. The present invention also relates to methods for treating bacterial infections in mammala. The present invention also relates to methods for decreasing bacterial quantity in a biological sample.

REFERENCES:
patent: 4174400 (1979-11-01), Mrozik
patent: 4512998 (1985-04-01), Nafissi-Varchei
patent: 5529998 (1996-06-01), Habich et al.
patent: 0 738 726 (1996-10-01), None
patent: 1 055 668 (2000-11-01), None
patent: WO 99/35155 (1999-07-01), None
patent: WO 00/49015 (2000-08-01), None
patent: WO 00/71522 (2000-11-01), None
Pea et al., PubMed Abstract (Clin Pharmacokinet. 44(10):1009-34) 2005.
Snyder et al., PubMed Abstract (J Med Liban. 48(4):208-14), Jul.-Aug. 2000.
U.S. Appl. No. 10/015,332, filed Dec. 12, 2001, Anne-Laure Grillot et al.
Singh, S.K., et al., “Studies in antiparastic agents: Part 13—Synthtesis of 4-aryl-2-substitutedamino-thiazoles as potential anthelmintics,”Indian J. Chem., 28B(9):786-789 (1989).
Beers, M. H., and Berkow, R., “The Merck Manual of Diagnosis and Therapy”, 7thEdition, Chapter 156—Bacteremia and Septic Shock, Merck Research Laboratories, Whitehouse Station, NJ pp. 1143-1147 (1999).
Nicolaus B. J. R., “Symbiotic Approach to Drug Design,” Decision Making in Drug Research, pp. 173-186 (1983).
Kus, C., “Synthesis and antimicrobial activities of 5-fluoro-1, 2, 6-trisubstituted benzimidazole carboxamide and acetamide derivatives,” Arch. Pharm. Pharm. Med. Chem. 334(11):361-365 (2001).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Gyrase inhibitors and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gyrase inhibitors and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gyrase inhibitors and uses thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2753527

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.