Drug – bio-affecting and body treating compositions – Chewing gum type
Patent
1979-03-12
1980-11-11
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Chewing gum type
426 4, 426 5, 426 6, 424 52, A61K 968
Patent
active
042332885
ABSTRACT:
A composition containing critical proportions of 3 to 5 parts filler, 25 to 35 parts chewing gum base, gum chicle or SBR synthetic rubber, a minimum amount of emulsifier and from 40 to 62 parts of a water based emulsified phase. The emulsified water phase contains 3 to 6 parts sweetener and dissolved, inorganic mineral salts, such as sodium, potassium, calcium and magnesium chlorides and potassium phosphates, at a concentration of about 1% to 3% of the water phase, which is in the physiological range to ameliorate medical conditions such as xerostoma by controlling release of the dilute mineral salt solution during chewing thereof. When saliva is lacking, the liquid may contain dissolved salts higher than the physiological level, with or without 2 to 30 parts per million fluoride ions, so as to prevent demineralization of teeth. Under the direct supervision of a physician or dentist, the fluoride ions (NaF, SnF.sub.2 or sodium fluorophosphate) may be increased to 500 to 1000 parts per million depending upon frequency of use. Other additives may be introduced to the water phase such as coating compositions for the teeth or medicants released to the digestive system. It is essential that the composition be packaged in a moisture-proof seal which can be accomplished with a foil coated wrapping inside a moisture barrier plastic, glass or metal container.
REFERENCES:
patent: 2627493 (1953-02-01), Merckel et al.
patent: 3085048 (1963-04-01), Bush
patent: 3639569 (1972-02-01), Medcalf
patent: 3992519 (1976-11-01), Hofmann
patent: 4151270 (1979-04-01), Ream
patent: 4154814 (1979-05-01), Hand
Handbook of Nonprescription Drugs, 5th Ed. (1977) Published by Am. Pharm. Assoc. Wash. D.C. pp. 249,250,259,260,262 & 263.
Robinson Douglas W.
Saffitz Abraham A.
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