Guanidinyl and related cell adhesion modulation compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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Details

514 20, 530331, A61K 3702, C07K 508, C07K 510

Patent

active

052602770

ABSTRACT:
Guanidinyl-containing compounds, and related compounds and salts, useful as cell receptor antagonists for modulating cell adhesion via integrin receptors and/or fibronectin receptors, are disclosed. Methods for synthesizing, testing, formulating, and using the compounds as therapeutic agents are also disclosed.

REFERENCES:
patent: 4879313 (1989-11-01), Tjoeng et al.
patent: 4952562 (1990-08-01), Klein et al.
patent: 5053392 (1991-10-01), Klein et al.
patent: 5053393 (1991-10-01), Tjoeng et al.
patent: 5061693 (1991-10-01), Nutt et al.

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