Guanidinothiazole derivatives containing alkylene bridges, and t

Details Guanidinothiazole derivatives containing alkylene bridges, and t Guanidinothiazole derivatives containing alkylene bridges, and t

1983-05-09

1986-04-08

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544332, 548183, 548184, 548185, 548187, 548190, 548192, 514272, 514275, 514369, 514370, 514371, C07D23902, A61K 31495

Patent

active

045814538

ABSTRACT:
The invention relates to guanidinothiazol derivatives of Formula (I) as defined herein, said compounds being useful for influencing lipid metabolism, as antithombotic agents and as antimycotic agents. Also included in the invention are compositions containing said guanidinothiazol derivatives of Formula (I) and the use of said compounds and compositions for treatment of the above-mentioned conditions. In addition, the invention includes methods for the manufacture of the guanidinothiazole derivatives of Formula (I).

REFERENCES:
Usui, Ann. Rep. Takeda Res. Lab., 1968, 27, 96-111.
Hans Beyer et al, Chem. Abst., vol. 57, 4643-4644.
Boedeker et al, Chem. Abst., vol. 84, 59284h.
Nabih et al, J. of Pharmaceutical Science, vol. 61, No. 6, 1972, pp. 967-968.
Beyer et al, Liebigs Ann. Chem., 748 (1971) pp. 109-122.
Usi, Chem. Abst., vol. 70 (1969) 77845g.
Rembarz et al, Chem. Abst., vol. 100 (1984) 6463h.

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