Guanidinocyclohexanecarboxylic acid derivatives

Details Guanidinocyclohexanecarboxylic acid derivatives Guanidinocyclohexanecarboxylic acid derivatives

1982-01-04

1984-08-14

Shippen, Michael L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

546174, 548510, 260465D, 424258, 424274, 424283, 424304, 424305, 549401, C07C12912

Patent

active

044658516

ABSTRACT:
A compound having the formula ##STR1## wherein R.sub.1 represents an indanyl, indolyl, quinolyl or chromonyl group, the group of the formula ##STR2## (in which R.sub.2 represents a halogen atom or a nitro group), or the group of the formula ##STR3## (in which R.sub.3 represents a halogen atom, or an alkyl, nitro, cyano, acetamino, aminosulfonyl, benzoyl, phenoxy or trifluoromethyl group, R.sub.4 represents a hydrogen or halogen atom, or an alkyl group, and R.sub.5 represents a hydrogen or halogen atom, or an alkyl group), or a pharmaceutically acceptable salt thereof. The compound is obtained by reacting 4-guanidinomethylcyclohexanecarboxylic acid or a reactive derivative thereof with a compound of the formula R.sub.1 --OH wherein R.sub.1 is the same as defined above, or a reactive derivative thereof.

REFERENCES:
patent: 3699149 (1972-10-01), Yamamura
patent: 4348410 (1982-09-01), Muramatsu

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