Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1988-07-28
1990-08-14
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514536, 514537, 560 34, A61K 31245, C07C27818
Patent
active
049488082
ABSTRACT:
A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. ##STR1## wherein X represents a group of the formula: ##STR2## in which Y is a group of the formula: --(CH.sub.2).sub.m--, m being an integer of 2 or 3, ##STR3## or a group of the formula:
Hishinuma Ieharu
Kawashima Hidetoshi
Kawata Tsutomu
Miyamoto Kaname
Miyazawa Shuhei
Eisai Co. Ltd.
Nucker Christine M.
Tsung Frederick F.
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