Guanidinobenzoic acid derivatives and process for their preparat

Details Guanidinobenzoic acid derivatives and process for their preparat Guanidinobenzoic acid derivatives and process for their preparat

1980-02-22

1981-08-11

Breitenstein, G. T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

26050111, 26050112, 560 34, A61K 31245, C07C10156

Patent

active

042834180

ABSTRACT:
Guanidinobenzoic acid derivatives represented by the general formula [I] ##STR1## wherein R.sup.1, R.sup.2 and Z are as defined hereinafter, having antiplasmin and anti-trypsin activities and process for their preparation as well as a pharmaceutical composition and a method of inhibiting the activity of plasmin and trypsin is disclosed.

REFERENCES:
patent: 4021472 (1977-05-01), Fujii et al.
Fujii et al., "Chem. Absts.", 88, 50530(k), 1978.
Okamoto et al., Keio Journal of Medicine, 11, 105, (1962).
Kassel et al., J. Biol. Chemistry, 238, 3274, (1963).

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