Guanidinealkyl-1,1-bisphosphonic acid derivatives process for th

Details Guanidinealkyl-1,1-bisphosphonic acid derivatives process for th Guanidinealkyl-1,1-bisphosphonic acid derivatives process for th

1994-11-23

1996-03-12

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546248, A61K 31445, C07D21110

Patent

active

054986176

ABSTRACT:
Guanidinealkyl-1,1-bisphosphonic acid derivatives, process for their preparation and their use
Compounds of the tautomeric formula Ia, Ib or Ic, ##STR1## where R is a radical of the formula ##STR2## are effective compounds for the treatment and prophylaxis of degenerative bone disorders. They are used as pharmaceuticals.

REFERENCES:
patent: 4255572 (1981-03-01), Kruger et al.
patent: 4927814 (1990-05-01), Gall et al.
patent: 4942157 (1990-07-01), Gall et al.
patent: 5294608 (1994-03-01), Lang et al.
patent: 5395826 (1995-03-01), Naumann et al.
Abstract of Isomura et al., Heterocycle-Substituted Bis(phosphonic acid Derivatives and Bone Absorption Inhibitors Containing Them, Chemical Abstracts, 113(9):812, 78695b (1990).
"New Methods of Preparative Organic Chemistry IV, Synthesis Using Heterocyclic Amides (Azolides)", Staab, H. A., Angew. Chem. Internat. Edit. 1(7):351-367 (1962).
Advanced Organic Chemistry-Reactions, Mechanisms, and Structure March J., Fourth Edition, pp. 348-352 (1983).

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