Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1976-09-19
1977-09-27
Schwartz, Gerald A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
2602949, 260295G, 260296R, 260465E, 560 34, 26050114, 260565, 424263, 424309, 424316, 424326, C07C12912
Patent
active
040512568
ABSTRACT:
Guanidine derivatives of the formula: ##STR1## in which R.sup.1 is a cyclohexyl, adamantyl, bicycloheptanyl, bicycloheptenyl, tricycloheptanyl or tetracyclononanyl radical and R.sup.2 is a phenyl or pyridyl radical optionally substituted by 1 or 2 halogen atoms, or alkyl, cyanoalkyl, alkoxycarbonyl or amino radicals, and the pharmaceutically-acceptable acid-addition salts thereof, active against rhinoviruses, are disclosed, along with processes for their manufacture, compositions containing them, a method of combatting rhinoviral infections and a method of selectively killing rhinoviruses in a mixed virus population.
REFERENCES:
geluk et al., J. Med. Chem. vol. 12, pp. 712-715 (1969).
Imperial Chemical Industries Limited
Schwartz Gerald A.
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