Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1997-01-21
Datlow, Philip I.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546141, 546246, A61K 3147, C07D40112
Patent
active
055959997
ABSTRACT:
Compounds of the formula ##STR1## wherein L, M, R, T and X are set forth in the description, as well as hydrates or solvates thereof, which inhibit thrombin-induced platelet aggregation and clotting of fibrinogen in plasma, are described. The compounds of formula I are prepared by amidination or, depending on whether L is NH or O, by amide formation or esterification.
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Ackermann Jean
Banner David
Gubernator Klaus
Hadvary Paul
Hilpert Kurt
Datlow Philip I.
Epstein William H.
Hoffmann-La Roche Inc.
Johnston George W.
Pokras Bruce A.
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