Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-09-17
1998-06-09
Gupta, Yogendra N.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514212, 5142372, 514326, 540481, 540544, 540597, 544129, 546208, A61K 3155, A61K 31445, C07D26710, C07D21122
Patent
active
057634360
ABSTRACT:
Compounds of the formula ##STR1## wherein L, M, R, T and X are set forth in the description, as well as hydrates or solvates thereof, which inhibit thrombin-induced platelet aggregation and clotting of fibrinogen in plasma, are described. The compounds of formula I are prepared by amidination or, depending on whether L is NH or O, by amide formation or esterification.
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Ackermann Jean
Banner David
Gubernator Klaus
Hadvary Paul
Hilpert Kurt
Epstein William H.
Gupta Yogendra N.
Hoffmann-La Roche Inc.
Johnston George W.
Parise John P.
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