Guanidine derivatives

Details Guanidine derivatives Guanidine derivatives

1977-05-31

1979-02-20

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

26032643, 424251, 424273R, 544331, 544332, 548316, C07D20706, H61K 3140, C07D20708, C07D20710

Patent

active

041407938

ABSTRACT:
The invention concerns novel guanidine derivatives of the general formula (I) ##STR1## or pharmaceutically acceptable acid addition salts thereof, where.circle.Nrepresents ##STR2## wherein R.sup.1 and R.sup.2 each represent hydrogen, lower alkyl, trifluoromethyl or halogen and R.sup.11 and R.sup.12 each represent hydrogen, lower alkyl, trifluoromethyl or halogen with the proviso that when one or both R.sup.11 or R.sup.12 groups represent halogen then R.sup.1 and R.sup.2 each represent lower alkyl, trifluoromethyl or halogen, R.sup.9 and R.sup.10 each represent hydrogen, lower alkyl or trifluoromethyl and R.sup.13 and R.sup.14 each represent hydrogen, lower alkyl, trifuoromethyl or halogen with the proviso that when one or both R.sup.13 and R.sup.14 groups represent halogen then R.sup.9 and R.sup.10 each represent lower alkyl or trifluoromethyl and R.sup.7 and R.sup.8 each represent hydrogen or lower alkyl and R.sup.3, R.sup.4, R.sup.5 and R.sup.6 each represent hydrogen or lower alkyl or R.sup.4 and R.sup.6 are each hydrogen and R.sup.3 and R.sup.5 together represent dimethylene or trimethylene. The guanidine derivatives lower blood pressure in warm-blooded animals.

REFERENCES:
patent: 3189601 (1965-06-01), Mull

Affiliated with

Also associated with

Rating

Guanidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Guanidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Guanidine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-258829