Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – Transgenic nonhuman animal
Reexamination Certificate
2007-09-04
2007-09-04
Crouch, Deborah (Department: 1632)
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
Transgenic nonhuman animal
C800S003000, C800S009000, C800S012000, C800S025000
Reexamination Certificate
active
10276460
ABSTRACT:
A transgenic animal in which GSK-3β protein is over-expressed is useful as a model for neurodegenerative disease.
REFERENCES:
patent: WO95/05466 (1995-02-01), None
patent: WO98/03644 (1998-01-01), None
patent: WO 01/02552 (2001-01-01), None
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Lucas et al. (2001) “Decreased Nuclear B-Catenin, Tau Hyperphosphorylation and Neurodigeneration in GSK-3B Conditional Transgenic Mice” EMBO J. 20(1/2):27-39.
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De Grado Jesús Avila
Lozano José Javier Lucas
Perez Félix Hernandez
Consejo Superior de Investigaciones Clentificas
Crouch Deborah
Universidad Autonoma de Madrid (UAM)
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