GSK-3 inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C546S119000

Reexamination Certificate

active

10874962

ABSTRACT:
The invention provides compounds of formula (I)the stereoisomers and prodrugs thereof, and the pharmaceutically acceptable salts of the compounds, stereoisomers, and prodrugs, wherein R1, R2, and R3are as defined herein; pharmaceutical compositions thereof; and use thereof in the treatment of, inter alia, conditions, diseases, and symptoms such as diabetes, dementia, Alzheimer's Disease, stroke, schizophrenia, depression, hair loss, and cancer.

REFERENCES:
patent: 4020072 (1977-04-01), Hoehn
patent: 138773 (1979-11-01), None
patent: WO 0224694 (2002-03-01), None
patent: WO 03045949 (2003-06-01), None
Wolff, Manfred E. “Burger's Medicinal Chemistry, 5ed, Part I”, John Wiley & Sons, 1995, pp. 975-977.
Banker (Modern Pharmaceutics) Banker, G.S. et al, “Modern Pharmaceutics, 3ed.”, Marcel Dekker, New York, 1996, pp. 451 and 596.
Quiroga et al ‘Synthesis, molecular structure and tautomerism of 1(2)H-dihydropyrazolo[3,4-b]pyridin-6-ones’ CA 131:116184 (1999).
Dorn, H. et al., Journal f. prakt. Chemie. Band, vol. 324, pp. 557-562, Heft 4, 1982, “Eindeutige Synthese des 4,7-Dihydro-4-oxo-1H-pryzolo[3,4-b]pyridins Bemerkungen zur,,(N-C)-Umlagerung von (2-Alkoxycarbonyl-vinly-amino)pyrazolen”.
Ibrahim, M.K.A. et al., J. Indian Chem. Soc., vol. 74, pp. 206-208, Mar. 1977, “Synthesis of Pyrazoles and Fused Pyrazoles. Novel Synthesis of Pyrano[2,3-c]pyrazole, Thieno[2,3-c]pyrazole and Pyrazolo[3,4-b]pyridine Derivatives”.
Balicki, Roman, Polish Journal of Chemistry, Part X, vol. 56, 1273, pp. 789-797, 1983, “Studies in the Field of Nitrogen Heterocyclic Compounds. Part XI*. Abnormal Cyclocondensation of Ethyl 4,4,4-Trifluoroacetoacetate with Aminopyrazoles”.

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