Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-04-09
1987-08-25
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514812, A61K 3141
Patent
active
046893326
ABSTRACT:
A method for regulating the growth processes in a myriad of cells, tissues, organ systems and unicellular and multicellular organisms including plants, animals and man by the administration of effective amounts of the opioid antagonists naloxone, naltrexone, their analogs metabolites derivatives, and/or mixtures thereof. At the cellular level, the growth processes entail all mitotic events and related processes including cell proliferation, as well as cell migration and cell differentiation, and at the somatic or organismal level, anatomical, behavioral and neurological development, metamorphisis and maturation. Growth regulation can be effected in vivo and/or in vitro.
REFERENCES:
Chem Abst., 88:183495z; Chihara et al., 1978.
Chem Abst., 93:37699f, Grandison et al., 1980.
Chem Abst., 100:18090x, Zagon et al., 1984.
Chem Abst., 103:207085x, Ilinskii et al., 1985.
"Naltrexone Modulates Growth in Infant Rats", Ian S. Zagon and Patricia J. McLaughlin, Life Sciences, vol. 33, pp. 2449-2545, 1983 Pergamon Press Ltd.
McLaughlin Patricia J.
Zagon Ian S.
Brown Johnnie R.
Research Corporation
Rollins Jr. John W.
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