Growth promotion

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

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2603458R, A61K 3169

Patent

active

042255937

ABSTRACT:
This invention relates to the use of aplasmomycin, boromycin and acylated and hydrogenated derivatives thereof for modifying rumen metabolism in domestic ruminant animals, by reducing the proportion of methane formed, and increasing the proportion of propionate at the expense of methane and/or acetate. This modification of rumen metabolism is believed to improve growth in ruminant animals. The disclosure also describes compositions which may be used in the claimed method, an improved process for the production of aplasmomycin, and novel analogs of aplasmomycin and boromycin together with processes for their manufacture.

REFERENCES:
patent: 3864479 (1975-02-01), Miller et al.
Okami et al., "J. of Antibiotics", vol. XXIX, (1976), pp. 1019-1025.
Kitahata, "J. of Antibiotics", vol. XXX, (1977), pp. 714-719.
Hutter et al., "Helvetica Chimica Acta", vol. 50, (1967), pp. 1533-1539.
Dunitz et al., "Helvetica Chimica Acta", vol. 54, (1971), pp. 1709-1713.

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