Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology
Reexamination Certificate
2011-03-01
2011-03-01
Nickol, Gary B. (Department: 1647)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Method of regulating cell metabolism or physiology
C435S325000, C435S366000, C435S368000, C435S372000, C435S404000
Reexamination Certificate
active
07897388
ABSTRACT:
This invention is concerned with stem cells derived from umbilical cord blood serum and a method for growing human embryonic stem cells and adult cells comprising sera separated from clotted umbilical cord blood, including growing and differentiating cord blood stem cells into neural precursors, comprising transdifferentiating CD34+, CD45+ and CD133+ stem cells from mononuclear cells derived from umbilical cord blood to neural precursors. The stem cells obtained from the umbilical cord include pluripotent stem and progenitor cell population of mononuclear cells, and separating pluripotent stem and progenitor cell population of mononuclear cells obtained from the umbilical cord blood. A magnetic cell separator is used to separate out cells which contain a CD marker and then expanding the cells in a medium containing retinoic acid as a differentiating agent supplemented with one or more growth factors BDNF, GDNF, NGF and FGF in presence of cord blood serum. The invention is also concerned with the transplantation and repair of nerve damage, strokes, spinal injury, Parkinson's and Alzheimer's, prepared with a media for culturing umbilical cord blood stem cells in umbilical cord serum.
REFERENCES:
patent: 5411883 (1995-05-01), Boss et al.
patent: 6475483 (2002-11-01), Steinman et al.
patent: 7098027 (2006-08-01), Honmou et al.
patent: 7160724 (2007-01-01), Sanberg et al.
patent: 2002/0164794 (2002-11-01), Wernet
patent: 2003/0039952 (2003-02-01), Peled
Tondreau et al., Stem Cells, vol. 23, Issue 8, pp. 1105-1112, (2005.).
Shetty Prathibha
Viswanathan Chandra
Gamett Daniel C
Lackenbach & Siegel LLP
Nickol Gary B.
Nissen J. Harold
Reliance Life Sciences Pvt. Ltd.
LandOfFree
Growth of neural precursor cells using umbilical cord blood... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Growth of neural precursor cells using umbilical cord blood..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Growth of neural precursor cells using umbilical cord blood... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2688597