Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Endocrine system – other than the thymus gland
Patent
1996-03-29
1997-10-28
Chan, Christina
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Endocrine system, other than the thymus gland
424556, 424572, 435350, 435351, 435352, 435363, 435366, 435395, 435402, 514 3, 514 4, A61K 3539, A61K 3828, C12N 506, C12N 508
Patent
active
056815875
ABSTRACT:
A method of increasing the number of adult pancreatic islet cells available for transplantation by contacting the cells with laminin 5 extracellular matrix. When contacted with the deposited matrix produced by 804G rat bladder carcinoma cells, a 1,500 fold increase in cell number is observed after three passages in culture. Islet cell expansion also occurs when cells are contacted with 804G soluble matrix. The expanded islet cells contain insulin and respond to glucose challenge.
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Grzesiak John J.
Halberstadt Craig
Zimber Michael
Chan Christina
Desmos, Inc.
VanderVegt F. Pierre
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